The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Prostate Cancer Susceptibility Loci ¹

Added AMACR ² as a new subsection.

Added Zheng et al. as reference 135 ³.

Added Genome-wide Association Studies ⁴ as a new subsection.

Polymorphisms and Prostate Cancer Susceptibility ⁵

Added text ⁶ about a study that indicated short AR repeat variants do not contribute significantly to the risk of prostate cancer in African-American men (cited Lange et al., Panz et al., and Gilligan et al. as references 24, 25, and 26, respectively).

Added text ⁷ about a study that found a cumulative association of five SNPs increased the risk of prostate cancer (cited Zheng et al. as reference 38).

Added text ⁸ about a study that found carriers of a single nucleotide polymorphism (160→A allele) in the E-cadherin gene were at 30% increased risk of prostate cancer (cited Wang et al. as reference 39).

Psychosocial Issues in Prostate Cancer ⁹

Added text ¹⁰ about a study of African American men who completed a nine-item telephone questionnaire assessing knowledge about hereditary prostate cancer (cited Weinrich et al. as reference 2).