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Endometrial Cancer Screening (PDQ®)
Patient VersionHealth Professional VersionLast Modified: 05/02/2008



What is screening?






General Information About Endometrial Cancer







Endometrial Cancer Screening






Risks of Endometrial Cancer Screening






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Changes to This Summary (05/02/2008)






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Key Points for This Section


Tests are used to screen for different types of cancer.

Some screening tests are used because they have been shown to be helpful both in finding cancers early and decreasing the chance of dying from these cancers. Other tests are used because they have been shown to find cancer in some people; however, it has not been proven in clinical trials that use of these tests will decrease the risk of dying from cancer.

Scientists study screening tests to find those with the fewest risks and most benefits. Cancer screening trials also are meant to show whether early detection (finding cancer before it causes symptoms) decreases a person's chance of dying from the disease. For some types of cancer, finding and treating the disease at an early stage may result in a better chance of recovery.

There is no standard or routine screening test for endometrial cancer.

Screening for endometrial cancer is under study and there are screening clinical trials taking place in many parts of the country. Information about ongoing clinical trials is available from the NCI Web site.

Tests that may detect (find) endometrial cancer are being studied:

Pap test

A Pap test is a procedure to collect cells from the surface of the cervix and vagina. A piece of cotton, a brush, or a small wooden stick is used to gently scrape cells from the cervix and vagina. The cells are viewed under a microscope to find out if they are abnormal. This procedure is also called a Pap smear.

Pap tests are not used to screen for endometrial cancer; however, Pap test results sometimes show signs of an abnormal endometrium (lining of the uterus). Follow-up tests may detect endometrial cancer.

Transvaginal ultrasound

Transvaginal ultrasound is a procedure used to examine the vagina, uterus, fallopian tubes, and bladder. An ultrasound transducer (probe) is inserted into the vagina and used to bounce high-energy sound waves (ultrasound) off internal tissues or organs and make echoes. The echoes form a picture of body tissues called a sonogram. The doctor can identify tumors by looking at the sonogram. This test is commonly used to examine women who have abnormal vaginal bleeding.

Endometrial sampling

Endometrial sampling is the removal of tissue from the endometrium by inserting a thin, flexible tube through the cervix and into the uterus. The tube is used to gently scrape a small amount of tissue from the endometrium and then remove the tissue samples. A pathologist views the tissue under a microscope to look for cancer cells. This test is commonly used to examine women who have abnormal vaginal bleeding.

If you have abnormal vaginal bleeding, check with your doctor.

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