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Childhood Rhabdomyosarcoma Treatment (PDQ®)
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Table 3. COG-STS Surgico-pathologic Group System

Group  Definition 
I (Approximately 13% of all patients are in this group.) A localized tumor that is completely removed with pathologically clear margins and no regional lymph node involvement.
II (Approximately 20% of all patients are in this group.) A localized tumor that is grossly removed with (a) microscopic disease at the margin, (b) involved, grossly removed regional lymph nodes, or (c) both (a) and (b).
III (Approximately 48% of all patients are in this group.) A localized tumor with gross residual disease after incomplete removal or biopsy only.
IV (Approximately 18% of all patients are in this group.) Distant metastases are present at diagnosis.


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