Agent/Agent Class/Modality	Affected Body System
Anthracyclines	Circulatory (Cardiac)
	Respiratory (Pulmonary)
Alkylating agents	Reproductive (Gonadal)
	Second malignant neoplasms
Topoisomerase II inhibitors	Second malignant neoplasms
Platinums	Urinary (Renal)
	Special senses (Hearing)
	Second malignant neoplasms
Corticosteroids	Central nervous system
	Musculoskeletal (Bone and body composition)
	Musculoskeletal (Obesity)
Intrathecal chemotherapy	Central nervous system
Bleomycin	Respiratory (Pulmonary)
Methotrexate	Central nervous system
Vincristine	Digestive (Dental)
Thioguanine	Digestive (Hepatic)