Treatment of recurrent mycosis fungoides and the Sézary syndrome may include the following:

• Radiation therapy to skin lesions or all the skin on the body (TSEB).
• PUVA therapy.
• Topical chemotherapy.
• A clinical trial of PUVA therapy with interferon alfa.
• A clinical trial of extracorporeal photochemotherapy.
• A clinical trial of radiolabeled monoclonal antibody therapy.
• A clinical trial of interleukin-2.
• A clinical trial of retinoid therapy.
• A clinical trial of chemotherapy.
• A clinical trial of high-dose chemotherapy with stem cell transplant.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with recurrent mycosis fungoides/Sezary syndrome. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

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