De Novo Myelodysplastic Syndromes
Secondary Myelodysplastic Syndromes
Previously Treated Myelodysplastic Syndromes

A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.

Treatment of de novo myelodysplastic syndromes may include the following:

• Supportive care with transfusion therapy.
• High-dose chemotherapy with stem cell transplant using stem cells from a donor.
• Supportive care with growth factor therapy.
• Chemotherapy with azacitidine, decitabine, or other anticancer drugs.
• Supportive care with drug therapy.
• A clinical trial of a new anticancer drug.
• A clinical trial of low- dose chemotherapy with stem cell transplant using stem cells from a donor.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with de novo myelodysplastic syndromes.

Treatment of secondary myelodysplastic syndromes may include the following:

• Supportive care with transfusion therapy.
• Supportive care with growth factor therapy.
• Chemotherapy with azacitidine or other anticancer drugs.
• Chemotherapy with stem cell transplant using stem cells from a donor.
• A clinical trial of chemotherapy.
• A clinical trial of low- dose chemotherapy with stem cell transplant using stem cells from a donor.
• A clinical trial of supportive care with drug therapy.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with secondary myelodysplastic syndromes.

Treatment of previously treated myelodysplastic syndromes may include the following:

• High-dose chemotherapy with stem cell transplant using stem cells from a donor.
• Chemotherapy with azacitidine or decitabine.
• Supportive care with transfusion therapy, growth factor therapy, and/or drug therapy.
• A clinical trial of low- dose chemotherapy with stem cell transplant using stem cells from a donor.
• A clinical trial of new drug therapy.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with previously treated myelodysplastic syndromes.

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