Treatment of recurrent pancreatic cancer may include the following:

• Chemotherapy.
• Palliative surgery or stent placement to bypass blocked areas in ducts or the small intestine.
• Palliative radiation therapy.
• Other palliative medical care to reduce symptoms, such as nerve blocks to relieve pain.
• Clinical trials of chemotherapy, new anticancer therapies, or biologic therapy.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with recurrent pancreatic cancer ¹.

Glossary Terms

Treatment to boost or restore the ability of the immune system to fight cancer, infections, and other diseases. Also used to lessen certain side effects that may be caused by some cancer treatments. Agents used in biological therapy include monoclonal antibodies, growth factors, and vaccines. These agents may also have a direct antitumor effect. Also called immunotherapy, biotherapy, biological response modifier therapy, and BRM therapy.

A surgical procedure in which the doctor creates a new pathway for the flow of body fluids.

Treatment with drugs that kill cancer cells.

A type of research study that tests how well new medical approaches work in people. These studies test new methods of screening, prevention, diagnosis, or treatment of a disease. Also called a clinical study.

In medicine, a tube or vessel of the body through which fluids pass.

A procedure in which medicine is injected directly into or around a nerve or into the spine to block pain.

Treatment given to relieve the symptoms and reduce the suffering caused by cancer and other life-threatening diseases. Palliative cancer therapies are given together with other cancer treatments, from the time of diagnosis, through treatment, survivorship, recurrent or advanced disease, and at the end of life.

A disease in which malignant (cancer) cells are found in the tissues of the pancreas. Also called exocrine cancer.

The use of high-energy radiation from x-rays, gamma rays, neutrons, protons, and other sources to kill cancer cells and shrink tumors. Radiation may come from a machine outside the body (external-beam radiation therapy), or it may come from radioactive material placed in the body near cancer cells (internal radiation therapy). Systemic radiation therapy uses a radioactive substance, such as a radiolabeled monoclonal antibody, that travels in the blood to tissues throughout the body. Also called radiotherapy and irradiation.

Cancer that has recurred (come back), usually after a period of time during which the cancer could not be detected. The cancer may come back to the same place as the original (primary) tumor or to another place in the body. Also called recurrence.

The part of the digestive tract that is located between the stomach and the large intestine.

A device placed in a body structure (such as a blood vessel or the gastrointestinal tract) to keep the structure open.

A procedure to remove or repair a part of the body or to find out whether disease is present. An operation.

An indication that a person has a condition or disease. Some examples of symptoms are headache, fever, fatigue, nausea, vomiting, and pain.