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Clinical Trial Results - Progress in Cancer Care
These summaries highlight recently released results from cancer clinical trials. The findings are significant enough that they are likely to influence your medical care.
The summaries are listed in reverse chronological order. You may also use the navigation tools on the left to search the summaries by keyword or type of cancer.
1. Paclitaxel Versus Docetaxel for Early Breast Cancer
(Posted: 04/30/2008) - Weekly treatment with the drug paclitaxel (Taxol®) in addition to standard chemotherapy proved most effective in extending overall survival among women with early-stage breast cancer, according to the April 17, 2008, New England Journal of Medicine.
2. Cisplatin No Better than Standard Therapy for Anal Canal Cancer
(Posted: 04/30/2008) - Replacing mitomycin with cisplatin in chemoradiotherapy for cancer of the anal canal failed to improve either disease-free or overall survival and resulted in more patients needing colostomies, according to a study in the April 23, 2008, Journal of the American Medical Association.
3. Celecoxib Reduces Risk of Precancerous Colorectal Polyps: Five-Year Results of APC Trial
(Posted: 04/23/2008) - The five-year results of the Adenoma Prevention with Celecoxib (APC) trial indicate that two years after daily use of celecoxib (Celebrex®) has ended, there continues to be a modest reduction in the recurrence of colorectal polyps, according to a presentation at the 2008 American Association for Cancer Research annual meeting.
4. IV Iron Effective in Treating Chemotherapy-Induced Anemia
(Posted: 04/21/2008) - Two studies in the April 1, 2008, Journal of Clinical Oncology found that intravenous iron significantly improves hemoglobin levels in patients taking erythropoietin-stimulating agents (ESAs) for chemotherapy-induced anemia compared with ESAs alone or ESAs plus oral iron.
5. Drug Combination Cuts Risk of Advanced Colon Polyps
(Posted: 04/21/2008) - Low doses of two chemopreventive agents are highly effective at preventing the recurrence of the lesions that are often precursors to colorectal cancer, according to results presented at the 2008 American Association for Cancer Research annual meeting.
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