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Clinical Trial Results

Summaries of Newsworthy Clinical Trial Results

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Related Pages
Prostate Cancer Home Page 1
NCI's gateway for information about prostate cancer.

Search for Clinical Trials 2
NCI's PDQ® Cancer Clinical Trials Registry.
Prostate Cancer Trial Results
1.  Denosumab Keeps Bones Strong during Prostate Cancer Treatment 3
(Posted: 10/28/2009) - Treatment with the monoclonal antibody denosumab increased bone mineral density (BMD) and reduced the risk of fractures in men who received a common treatment for prostate cancer that had not spread to other parts of the body, according to the results of a large, placebo-controlled clinical trial published in the August 20 New England Journal of Medicine.

2.  U.S. Cancer Screening Trial Shows No Early Mortality Benefit from Annual Prostate Cancer Screening 4
(Posted: 03/18/2009) - Six annual screenings for prostate cancer led to more diagnoses of the disease, but no fewer prostate cancer deaths, according to a major new report from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial, a 17-year project of the NCI. The PLCO was designed to provide answers about the effectiveness of prostate cancer screening.

3.  Radiation Plus Hormone Therapy for Locally Advanced Prostate Cancer Improves Survival 5
(Posted: 02/03/2009) - Clinical trial results published online December 15, 2009, in The Lancet, affirms earlier studies showing that adding radiation therapy to hormone therapy (HT) is more effective than HT alone for locally advanced prostate cancer.

4.  Review of Prostate Cancer Prevention Study Shows No Benefit for Use of Selenium and Vitamin E Supplements 6
(Posted: 10/27/2008, Updated: 12/09/2008) - Initial, independent review of study data from the Selenium and Vitamin E Cancer Prevention Trial (SELECT), funded by the National Cancer Institute (NCI) and other institutes that comprise the National Institutes of Health shows that selenium and vitamin E supplements, taken either alone or together, did not prevent prostate cancer. The data also showed two concerning trends: a small but not statistically significant increase in the number of prostate cancer cases among the over 35,000 men age 50 and older in the trial taking only vitamin E and a small, but not statistically significant increase in the number of cases of adult onset diabetes in men taking only selenium.

5.  Studies Make Case for Finasteride to Prevent Prostate Cancer 7
(Posted: 06/24/2008) - Three new analyses of data from a large prostate cancer prevention trial bolster the case for finasteride as a preventive agent against prostate cancer, according to an article published online May 18, 2008, by the journal Cancer Prevention Research.
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Table of Links

1http://www.cancer.gov/cancertopics/types/prostate
2http://www.cancer.gov/clinicaltrials/search
3http://www.cancer.gov/clinicaltrials/results/denosumab-bmd-prostate1009
4http://www.cancer.gov/newscenter/pressreleases/PLCOProstateResults
5http://www.cancer.gov/clinicaltrials/results/hormoneRTX0209
6http://www.cancer.gov/newscenter/pressreleases/SELECTJAMAresults2008
7http://www.cancer.gov/clinicaltrials/results/PCPT0608
8http://www.cancer.gov/clinicaltrials/results/prostate?keyword=any+prostate&page
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9http://www.cancer.gov/clinicaltrials/results/prostate?keyword=any+prostate&page
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10http://www.cancer.gov/clinicaltrials/results/prostate?keyword=any+prostate&page
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