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1. International Breast Cancer Trials
(Posted: 02/29/2008) - Scientists have uncovered molecular and genetic approaches to identify specific genes, proteins, and molecular pathways that are important for cancer development, growth, and survival. Understanding these biological mechanisms and how they relate to cancer has been a key factor in the development and delivery of new biologic cancer therapies, especially for breast cancer, which is the most frequently diagnosed form of cancer in women worldwide.
2. The Global Burden of Cancer
(Posted: 12/20/2007) - The National Cancer Institute oversees the U.S. National Cancer Program, and is also involved in the promotion of global health and cancer control. The National Cancer Act of 1971 directed the NCI to collect, analyze, and disseminate research on the prevention, diagnosis and treatment of cancer, to share cancer research information globally, and to support research being conducted by highly qualified foreign nationals outside the United States, support collaborative research involving American and foreign participants, and support training of American scientists abroad and foreign scientists in the United States.
3. Second Cancers
(Posted: 01/24/2007) - Over 10 million people in the U.S. - about one in 30 - are cancer survivors. This growing population reflects advances in cancer detection and treatment. But with the greater number of survivors comes an increasing number of people living long enough to experience more than one type of cancer in their lifetime.
4. Minority Participation in Clinical Trials
(Posted: 09/06/2006) - Clinical trials are a critical resource for the discovery of new prevention, diagnostic and treatment methods for cancer, but participation in clinical trials by minorities, particularly African Americans and those living in rural areas is low.
5. Survivorship and the Changing Role of Palliative Care
(Posted: 07/25/2003, Updated: 09/01/2006) - Globally, there are an estimated 22.4 million people living with a history of cancer and approximately 9 million cancer survivors in the United States.
6. Tailored Cancer Therapy
(Posted: 05/23/2006) - Advances in genetic research are transforming cancer diagnosis, and treatments that are tailored to the specific molecular changes that drive tumor growth are now being developed. Because most cancers result from several genetic mutations, NCI is focusing on developing diagnostic tests that identify a number of genetic markers that can be used to predict a person's response to specific therapies and inform treatment decisions for these diseases.
7. Survivorship
(Posted: 04/11/2006) - There are now over 10 million cancer survivors in the United States, representing about four percent of all Americans -- a number that has been increasing every year for decades. As cancer survivors live longer, the effects of cancer treatments and additional health risks become more apparent.
8. Turning Molecules into Medicine
(Posted: 02/14/2006) - The National Cancer Institute (NCI) is committed to the discovery and development of new and effective therapies for cancer. As a result, about half of the drugs used to treat cancer today are due to NCI’s efforts. The Developmental Therapeutics Program (DTP), within the Division of Cancer Treatment and Diagnosis (DCTD) is the drug development arm of NCI. Working with academic scientists, clinicians and commercial companies, DTP has contributed to the rapid development of drugs and therapies to improve cancer treatment.
9. Improving Cancer Survival by Understanding Racial and Ethnic Disparities
(Posted: 11/30/2005) - Reducing cancer health disparities is one of the key challenges for the National Cancer Institute (NCI). In 1989, former Secretary of Health and Human Services, Louis Sullivan, M.D., organized the NCI Black Leadership Initiative, and formation of a Hispanic and Appalachian Leadership Initiative soon followed in 1992.
10. A New Understanding of Pain Management
(Posted: 11/02/2005) - Pain can be a harsh reality of cancer, whether the pain is related to a tumor or caused by treatment of the disease. Some studies show that 30 percent to 50 percent of patients undergoing active treatment for cancer and 70 percent of those with advanced stages of the disease experience significant levels of pain and may be reluctant to discuss their pain with their doctors.
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