Grants awarded by NCI under this announcement will be funded as Howard Temin Pathway to Independence Awards in Cancer Research.

The candidate's research proposal must include research on the etiology, pathogenesis, prevention, diagnosis, control and treatment of HUMAN cancer. The proposed research may involve model systems, including animal models. However, at some point during the grant period, the proposed research must include work on human cancer (includes human cancer cells or tissues).

Candidates must be able to identify an individual with extensive experience in human cancer research who can serve as a mentor for the initial mentored phase of this award.

In the mentored phase, NCI will support salaries up to $75,000, plus applicable fringe benefits, and up to $30,000 for research support costs for a 12-month budget period.

Use of Model Systems

The proposed research may include model systems, including animal models. However, at some point during the grant period, the proposed research must include work on human cancer. Work developing or refining model systems will be supported only if the proposed research objectives actively test the relevance of the model to human cancer.

Data Sharing

Under the NIH Data Sharing Policy, grantees are expected to engage in a timely release of final data sets that have been generated with NIH support for use by other researchers, provide a Data Sharing Plan that will achieve this objective, OR state why data sharing is not possible or appropriate. No Data Sharing Plan is required for the mentored phase of the K99 mechanism because it supports career development. However, during the un-mentored, independent phase of the grant (R00 award), grantees are responsible to share the data and provide an acceptable Data Sharing Plan to the NIH as part of their NIH grant support.

< Previous Section  |  Next Section >