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Cancer Education and Career Development Program (R25T)

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Introduction

NCI Special Notes

Funded R25T Grants

Submitting an Application

Peer Review Process

Frequently Asked Questions
Policy-Related
Application Process/Review Related
Policy/Post Award

NCI Staff Contacts

Introduction

The Cancer Education and Career Development Program (R25T) supports the development and implementation of curriculum-dependent programs to train predoctoral and postdoctoral candidates in cancer research settings that are highly inter-disciplinary and collaborative. This program is particularly applicable to cancer prevention and control, epidemiology, nutrition, and the behavioral and population sciences, but should also be considered by other interdisciplinary areas of research such as imaging and molecular diagnosis that will require sustained leadership, interdisciplinary research environments, and more than one mentor per program participant to achieve their education and research career development objectives.

The Principal Investigator must be an established investigator in a field relevant to the objectives and purpose of the Program and able to provide both administrative and scientific leadership. Candidates may be predoctoral or postdoctorals. They usually must be (see exception below) citizens or non-citizen nationals of the United States, or must have been lawfully admitted to the United States for permanent residence (i.e., in possession of a currently valid Alien Registration Receipt Card I-551, or other legal verification of such status), but, under exceptional circumstances, the R25T does allow for the training of foreign nationals. These require NCI approval of individuals on a case-by-case basis and would always depend upon the special international, collaborative nature of the research areas that the training and Career Development Program emphasizes.

The R25T grant mechanism provides up to five years of support and is renewable. These grants support salary (up to $20,000 per year for predoctorals and $75,000 per year for postdoctorals), research development support (up to $20,000 for predoctorals and up to $30,000 per year for postdoctorals), advertising and recruitment costs, ancillary personnel costs, and facilities and administrative costs (formerly called indirect costs).

Program Announcement

PAR-06-511 CANCER EDUCATION AND CAREER DEVELOPMENT PROGRAM (R25T)

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NCI Special Notes

This is an NCI-specific program announcement. For all of the policies governing this award mechanism, refer to the Program Announcement: PAR-06-511 CANCER EDUCATION AND CAREER DEVELOPMENT PROGRAM (R25T).

Data Sharing

Under the NIH Data Sharing Policy, grantees are expected to engage in a timely release of final data sets that have been generated with NIH support for use by other researchers, provide a Data Sharing Plan that will achieve this objective, OR state why data sharing is not possible or appropriate. No Data Sharing Plan is required for the R25T mechanism because it supports a training, rather than, a research grant. It supports salaries and other ancillary costs for individual trainees, but it does not provide support for the generation of research data, directly. With regard to the data generated by trainees working in research environments funded by NIH research grants, it is the responsibility of the institutions that are awarded these research grants to share the data and provide acceptable Data Sharing Plans to the NIH as part of the research application.

Recommended Tables

Suggested tabular formats for presenting data on trainees are provided for your convenience. "Click on" TABLES (Word for Windows) or TABLES (PDF), which ever you prefer, to download this information.

Special Institutional Statement Regarding Human Subjects Research Under R25T Support

The National Cancer Institute (NCI) Cancer Education and Career Development Program (R25T) must be in compliance with all NIH/NCI policies pertaining to the use of human subjects. These policies apply to all research involving human subjects, not just clinical trials. The R25T is a training and career development grant in which candidate positions are filled at the discretion of the institution and assignment of candidate positions is generally not known at the time of application or at the time of an award. Due to this uncertainty, the word "Indefinite" should be placed in the box for IRB review date on the face page of the application and the applicant institution must provide in the submitted grant application a Special Statement on Human Subjects Research.

The complete Special Institutional Statement Regarding Human Subjects Research Under R25T Support may be accessed by clicking R25T Special Institutional Statement Regarding Human Subjects Research.

Inquiries:

Inquiries are encouraged, and the opportunity to clarify any issues or questions is welcome. Inquiries should be sent to:

Dr. Dorkina Myrick
Cancer Training Branch
National Cancer Institute
6116 Executive Boulevard, Suite 7019
Rockville, MD 20852 (overnight mail)
Bethesda, MD 20892?8346 (regular mail)
Telephone: (301) 496-8580
FAX: (301) 402-4472
Email: myrickd@mail.nih.gov

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Funded R25T Grants

Grant Number Principal Investigator Project Title Organization
5R25CA078447-07 ALBERTS, DAVID S Cancer Prevention and Control Training Grant UNIVERSITY OF ARIZONA
5R25CA087949-07 Bastani, Roshan UCLA Cancer Education and Career Development Program UNIVERSITY OF CALIFORNIA LOS ANGELES
5R25CA101871-04 BLAIR, IAN A Training Program in Cancer Pharmacology UNIVERSITY OF PENNSYLVANIA
5R25CA081137-07 BOVBJERG, DANA H. Cancer Prevention & Control: Multidisciplinary Training MOUNT SINAI SCHOOL OF MEDICINE OF NYU
2R25CA090301-06 Carroll, Raymond J Nutrition, Biostatistics and Bioinformatics TEXAS A&M UNIVERSITY SYSTEM
5R25CA057730-15 CHAMBERLAIN, ROBERT M. M.D. Anderson Education Program in Cancer Prevention UNIVERSITY OF TEXAS MD ANDERSON CAN CTR
1R25CA117865-01 CHAMPION, VICTORIA L Training in Research for Behavioral Oncology and Cancer Control Program INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
5R25CA098220-04 Dignan, Mark B. Kentucky Cancer Prevention and Control Training Program (R25T) UNIVERSITY OF KENTUCKY
5R25CA057726-16 EARP, JO ANNE L Cancer Control Education Program UNIVERSITY OF NORTH CAROLINA CHAPEL HILL
5R25CA094186-06 Elston, Robert C. TRAINING IN COMPUTATIONAL GENOMIC EPIDEMIOLOGY OF CANCER CASE WESTERN RESERVE UNIVERSITY
5R25CA057708-15 ENGSTROM, PAUL F. Career Development in Cancer Prevention Research at FCCC FOX CHASE CANCER CENTER
1R25CA118681-02 GAMBHIR, SANJIV S Stanford Molecular Imaging Scholars - SMIS STANFORD UNIVERSITY
5R25CA100600-04 Gapstur, Susan Postdoctoral Training Program in Cancer Epidemiology NORTHWESTERN UNIVERSITY
5R25CA092203-06 GAZELLE, G SCOTT Program in Cancer Outcomes Research Training (PCORT) MASSACHUSETTS GENERAL HOSPITAL
1R25CA113710-02 GLANTZ, STANTON A Postdoctoral training in tobacco control UNIVERSITY OF CALIFORNIA SAN FRANCISCO
5R25CA047888-19 HEIMBURGER, DOUG Cancer Prevention and Control Training Program UNIVERSITY OF ALABAMA AT BIRMINGHAM
5R25CA096945-05 HRICAK, HEDVIG Molecular Imaging: Training for Oncology SLOAN-KETTERING INSTITUTE FOR CANCER RES
5R25CA090314-05 JACOBSEN, PAUL B Behavioral Oncology Education and Career Development H. LEE MOFFITT CANCER CTR & RESEARCH INS
5R25CA093423-05 SIMINOFF, LAURA Pre- & Post-doctoral Training Program in Cancer Control VIRGINIA COMMONWEALTH UNIVERSITY
1R25CA114101-02 MARSHALL, JAMES R Epidemiologic and Basic Science in Cancer Prevention ROSWELL PARK CANCER INSTITUTE CORP
5R25CA090956-05 MASKARINEC, GERTRAUD Cancer Control Research Training in Multiethnic Hawaii UNIVERSITY OF HAWAII AT MANOA
5R25CA102618-03 MORROW, GARY Cancer Control Research Training Curriculum (R25T) UNIVERSITY OF ROCHESTER
5R25CA057712-14 MULLEN, PATRICIA DOLAN Behavioral Science Education Cancer Prevention/Control UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
5R25CA094061-05 NEUGUT, ALFRED I Training Program in Cancer Related Population Sciences COLUMBIA UNIVERSITY HEALTH SCIENCES
2R25CA092408-06 PATRICK, DONALD Biobehavioral Cancer Prevention and Control Training Program UNIVERSITY OF WASHINGTON
5R25CA098010-05 PHELPS, MICHAEL E UCLA Scholars in Oncologic Molecular Imaging(SOMI) UNIVERSITY OF CALIFORNIA LOS ANGELES
2R25CA092043-07 PRICE, RONALD R Multidisciplinary Research Training in Cancer Imaging VANDERBILT UNIVERSITY
2R25CA087972-07 RAKOWSKI, WILLIAM Transdisciplinary Cancer Control Research Training Grant MIRIAM HOSPITAL
1R25CA105012-02 RIVLIN, RICHARD S Collaborative Program in Nutrition and Cancer Prevention (PNCP) WEILL MEDICAL COLLEGE OF CORNELL UNIV
2R25CA090355-07 ROSE, HANNUM JULIA Prevention Research Educational Postdoctoral (PREP) Training Program CASE WESTERN RESERVE UNIVERSITY
5R25CA057711-14 SORENSEN, GLORIAN C Harvard Education Program in Cancer Prevention Control (R25T) HARVARD UNIVERSITY (SCH OF PUBLIC HLTH)
5R25CA098566-05 STAMPFER, MEIR J National Epidemiology of Cancer HARVARD UNIVERSITY (SCH OF PUBLIC HLTH)
5R25CA111898-03 STANGE, KURT C Practice-Based Research Network Cancer Control Training CASE WESTERN RESERVE UNIVERSITY
5R25CA057699-15 WARNECKE, RICHARD B CANCER EDUCATION AND CAREER DEVELOPMENT PROGRAM UNIVERSITY OF ILLINOIS AT CHICAGO
2R25CA057703-12 WEISSFELD, JOEL L Education Program in Cancer Prevention UNIVERSITY OF PITTSBURGH AT PITTSBURGH
2R25CA085771-07 WEITZEL, JEFFREY N Cancer Genetics Career Development Program CITY OF HOPE/BECKMAN RESEARCH INSTITUTE
5R25CA094880-06 WHITE, Emily Cancer Prevention Training-Nutrition, Exercise & Genetics UNIVERSITY OF WASHINGTON
5R25CA112355-03 WITTE, JOHN Training in Molecular & Genetic Epidemiology of Cancer UNIVERSITY OF CALIFORNIA SAN FRANCISCO

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Submitting an Application

Important Notice: Beginning October 1, 2006, all R25T applications should be submitted electronically through Grants.gov (http://www.grants.gov), using the SF424 Research and Related (R&R) forms and guide.

The R25T Program Announcement contains all instructions, information and links to documents and sources of information needed to submit an application for the R25T Award. Before submitting an application for the R25T Award, please read all information and follow the instructions found at the beginning of the R25T Program Announcement. When you select the link "Apply for Grant Electronically", you will be directed to the Grants.gov application download page. Please carefully read each paragraph on this page, in sequence, to avoid errors that may delay the application process.

Application Receipt Dates and Review Schedule

 Application Receipt Date: New, Renewal*, Revision*, and Resubmission* Initial Review Date Council Review Date Earliest Possible Start Date **
Receipt Cycle 1 January 25 June/July September/ October December
Receipt Cycle 2 May 25 October/November January/ February April
Receipt Cycle 3 September 25 February/March May/June July

* The move to electronic applications also has brought a change in terminology. The new Grants.gov terminology (included in the table above) corresponds to traditional NIH terms as follows:

  • New = new
  • Resubmission = a revised or amended application
  • Renewal = Competing Continuation
  • Continuation = Progress Report
  • Revision = Competing Supplement

If the application receipt date falls on a weekend, the application must be postmarked by the application receipt date and received at the Center for Scientific Review (CSR) by the following Monday.

If the application receipt date falls on a holiday, (but not on a weekend), the application must be postmarked by the application receipt date and received at CSR by the following day.

** Start dates are determined by the availability of NCI funds and may not occur until well after the earliest possible start date.

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Peer Review Process

Upon receipt, competing applications will be reviewed both by the Center for Scientific Review (CSR) and the National Cancer Institute (NCI) for completeness and for conformance to all eligibility requirements and special provisions and requirements. Incomplete applications will be returned to the applicant without further consideration.

Those applications judged to be complete and eligible will be evaluated, according to the review criteria listed in the Program Announcement, by a peer review group convened by the Division of Extramural Activities of the NCI. Applications will receive a second level review by the National Cancer Advisory Board (NCAB) to determine if the application meets the broad program needs and priorities of the NCI and the National Cancer Program.

For review criteria for the R25T grant mechanism, see the REVIEW CRITERIA section of the Program Announcement: PAR-06-511 CANCER EDUCATION AND CAREER DEVELOPMENT PROGRAM (R25T).

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Frequently Asked Questions

Policy-Related

1. How many trainees can be supported by an R25T grant?
The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.

2. Who should be on the Advisory Committee?
The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.

3. Since human subjects may be involved in the R25T program, must each trainee obtain his/her own IRB approval?
If the trainee will be participating in a larger research program that already has received IRB approval, new IRB approval is not needed. If the research proposed is not part of an ongoing research project with an IRB approval, new IRB approval is needed.

4. Is there a preference in the disciplines represented in the R25T program?
The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.

5. Can the trainee's salary be supplemented?
Yes, but only from non-PHS sources for work that is the same as being supported by the R25T. A trainee can be compensated for work while receiving salary from the R25T grant from any source as long as his/her total percent effort does not exceed 100 percent and the work is unrelated to the work being supported by the R25T.

6. If we have an existing curriculum that will serve the R25T program, can we still apply?
No. One of the main premises of this award is that there are not sufficient curricula available to compliment the research training experiences of an R25T program.

7. Can an R25T grant be awarded for less than 5 years?
The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.

8. What are the R25T requirements for Training in the Responsible Conduct of Research?
R25T grants do not have any mandatory requirements. However, it is strongly recommended that trainees deficient in this area who will be conducting clinical research with human subjects during their appointment obtain training in the responsible conduct of research.

9. How many faculty members should I have in the program?
You should have a sufficient number of faculty members to adequately address the proposed education and research training needs of the program. Trainees need multiple mentors, so the number of members who participate in the R25T program would be large. In addition, some faculty might participate in the design and implementation of specialized curriculum but not serve as mentors. The number of faculty involved could be large and diversified.

10. Should the mentors be mainly senior individuals?
The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.

Application Process/Review Related

11. Will my grant application be reviewed by a CSR peer review group?
No. Applications for the NCI Cancer Education and Career Development Program (R25T) are reviewed by an NCI initial review group that is composed specially to review multidisciplinary training and career development needs.

12. What should my application contain if it deals with human subjects, clinical trials or vertebrate animals?
Applicants should submit a Special Institutional Statement Regarding Human Subjects Research under R25T Support for all applications in which clinical trials are conducted. This statement must be submitted to NCI program staff for approval before the initial grant award can be issued and resubmitted with each "Application for a Continuation Grant."

The applicant must also include an abbreviated Data and Safety-Monitoring (DSM) plan showing that the sponsoring institution has established standards for data and safety monitoring of clinical trials.

Please follow the instructions in the Vertebrate Animals section of the instructions for preparing a SF 424 (R&R) Application Guide if vertebrate animals are used.

An award cannot be made without proper information on Gender and Minority Inclusion, Inclusion of Children, and Vertebrate Animals. The applicant must also obtain human subject IRB certification and provide this information to the NCI before an award is made. Furthermore, if appropriate, a detailed DSM plan must also be provided.

Policy/Award Related

13. Can the support provided for OTHER EXPENSES be used to offset costs incurred in advertising and recruiting for the program?
Yes. A small proportion of the budget can be used for advertising and recruiting the best candidates for the program. This kind of expense is usually not allowed on grants devoted to education, training, and career development. However, we expect that many of the programs supported by the R25T will involve multiple departments and schools and that recruitment to these very special programs will require additional efforts that are not part of the usual business of an institution.

14. Does the NCI R25T grant operate under Expanded Authority?
Yes, except in one area. Automatic carryover of unexpended funds is not permitted. If there is a need for carryover, prior approval by the Grants Administration Staff of the NCI is required. Under most circumstances, each R25T is fully funded each year and there is little need for carryovers.

15. If I have an R25T award and would like to ask for post award changes, how do I go about this?
You must contact the NCI Grants Administration official to determine the appropriate procedures to use in making a request for post award changes in your grant. This also applies to any of your needs that require a prior approval from the NCI. In general, you will have to make a request that is signed by you and a business official of your institution. After receiving the request, the Grants Administration official will consult with the NCI scientific program staff as necessary to determine whether the request can be approved.

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NCI Staff Contacts

For additional information regarding policies and/or guidance in preparing an application for the R25T Award, contact:

Dr. Shannon M. Lemrow
Program Director
Telephone: (301) 496-8580
Fax: (301) 402-4472
E-mail: lemrows@mail.nih.gov

Dr. Dorkina Myrick
Program Director
Telephone: (301) 496-8580
Fax: (301) 402-4472
E-mail: myrickd@mail.nih.gov

For information regarding review issues, contact:

Referral Officer
Division of Extramural Activities
Telephone: (301) 594-1403
Fax: (301) 402-0275

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